Figure 1. Pedigree structure

Filled symbols indicate individuals with RP in this family, and open circle or square indicate clinically unaffected subjects. Dotted circles indicate presumed and obligate carrier females. The numbers over the square or circle represent the number of the individual in the sibship. The bar over the symbol identifies individuals who were examined by one or more of the co-authors. IV-14 is the proband in this family. The "upside-down T" underneath III-2, III-8, III-10, and IV-9 indicates they had no children. Slashes indicate individuals who are deceased, the diamonds indicate stillbirths, and questions marks indicate family members whose health conditions were unavailable.