Table 1 of
Mullins, Mol Vis 2005;
11:509-517.Table 1 of
Mullins, Mol Vis 2005;
11:509-517.
Table 1. Histochemistry of CNVMs
Lectins employed in this study, their specificities, and patterns of labeling in three eyes with CNVMs are detailed in the table. Labeling of the disciform scar, basal laminar deposits (BlamD), and the CNV blood vessels is indicated. Labeling patterns are defined as follows: no labeling (-), weak, variable labeling (+/-), consistent labeling (+), and intense labeling (++). An asterisk indicates that the slide could not be assessed (Case 3 only).
Lectin Specificity Target Case 1 Case 2 Case 3
-------------- ---------------- ------ ------------ ------------ ------------
Canavalia α-linked mannose BlamD + + *
ensiformis Scar + + *
(Con A) CNV BV + + *
Dolichos α-linked Gal NAc BlamD - - -
bifloras (DBA) Scar - - -
CNV BV - ± subset -
Arachis galactosyl BlamD - - -
hypogea (PNA) (β-1,3) Scar - ++ ±
GalNAc CNV BV - + subset ±
Glycine max α- or β-linked BlamD - - -
(SBA) GalNAc Scar - - -
CNV BV + + +
Ulex europaeus α-linked fucose BlamD - - -
I (UEA-I) Scar - - -
CNV BV + + +
(normal BV+) (normal BV+) (normal BV+)
Pisum sativum oligosaccharides BlamD ± to + + *
(PSL) with α-linked Scar ++ ++ *
mannose CNV BV ± + *
Vicia villosa α- or β-linked BlamD + - -
(VVA) terminal of Scar - ± -
GalNAc CNV BV ± + +
Phaseolus Complex BlamD - ± *
vulgaris oligosaccharides Scar - ± *
(PHA-L) CNV BV ± in scar + *
Triticum GlcNAc BlamD ± (outer) + +
vulgaris Scar - - -
(Succinylated) CNV BV + subset ++ +
(sWGA)
Erythrina Galactose, esp. BlamD + regionally ± *
cristagalli gal (β-1,4) Scar - + *
(ECL) GalNAc CNV BV + in scar + *
Sambucus nigra NeuNAc alpha2-6 BlamD + + +
(EBL) Gal>NeuNAc Scar + - +
alpha2,3 Gal CNV BV + ± High
(normal BV+) (normal BV+) background
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