Figure 4 of
Hutcheson, Mol Vis 2005;
Figure 4. Denaturing high performance liquid chromatographs with corresponding base pair sequence changes
Example of denaturing high performance liquid chromatography waveform chromatographs with their corresponding sequences changes identified by direct sequencing. Samples C009 (wild type control), CR001 (daughter) and CR002 (father) are shown. The DHPLC waveforms show homoduplex controls in black and heteroduplex polymorphisms in color. The X-axis represents time in min; the y-axis is a measure of absorbency in μV. Sample sequence alteration is highlighted in blue.