Table 2 of
Chidlow, Mol Vis 2005;
11:387-396.Table 2 of
Chidlow, Mol Vis 2005;
11:387-396.
Table 2. Effects of ONT on total retinal mRNA levels of various trophic factors and GFAP
Percent increase in mRNA in ONT retina (relative to control retina). Data are expressed as mean±SEM. Statistical tests compared treated eyes to control eyes using Student's paired t-test (an asterisk indicates p<0.05, double asterisks indicate p<0.01, and triple asterisks indicate p<0.001), where n=6-9 (ONT 1 day), n=8-9 (ONT 3 days), n=12-20 (ONT 7 days), n=17-23 (ONT 21 days).
Time (days) FGF-2 CNTF BDNF NGF GDNF GFAP ------ ------------- ------------ ------------ ------------- --------- ------------- 1 14.2±11.5 17.4± 6.0 7.0 ±6.6 -13.9±13.1 -6.0±12.3 53.4±20.3 3 29.9± 4.1*** 28.9±13.2 33.4 ±6.7*** 19.2± 8.8 -5.6±12.8 70.3±15.0** 7 90.3±11.2*** 66.3±10.5*** -2.39±4.1 21.6± 5.3*** -8.1± 7.4 112.6±12.4*** 21 122.8±21.3*** 0.2± 5.9*** -8.1 ±3.5* 23.6± 7.1** 9.9± 9.3 76.6± 9.8*** |