Figure 4. Effect of BDNF on ONT induced loss of NF-L mRNA

The effect of intravitreal injection of BDNF (5 μg) on the ONT induced loss of NF-L mRNA in the rat retina after 7 days as measured by real-time RT-PCR (A) and conventional RT-PCR (B). In each case, values (bars represent means, error bars represent SEM) are normalized for GAPDH and expressed as a percentage of the control eye, where n=8. An asterisk (*) denotes p<0.001 using Student's unpaired t-test (ONT BDNF group compared to ONT vehicle group).