Figure 3. Expression of Crb2 mRNA in the adult mouse eye

A: The cellular expression of the Crb2 gene in the adult mouse eye was analyzed by mRNA in situ hybridizations. Crb2 is expressed in both the outer nuclear layer (ONL; photoreceptor cells) and inner nuclear layer (INL; horizontal, amacrine, and bipolar cells). The ganglion cell layer (GC), inner plexiform layer (IPL), and outer segments (OS) are labeled. The OPL collapses as an artifact of fixation/sectioning, but can be seen as a dark line between the INL and ONL. B: In some sections, Crb2 expression is also detected in some cells of the ganglion cell layer. These may represent displaced amacrine cells. C: Negative control experiment of the same retina.