Figure 2. Inhibition of basic fibroblast growth factor (bFGF) induced corneal angiogenesis by incorporation of vasostatin (VS) in a hydron polymer

A: Representative corneas after implantation of a bFGF pellet (90 ng per pellet; left panel) or a pellet containing bFGF plus VS (90 ng for bFGF and 180 ng for VS per pellet; right panel) for 7 days. The asterisk represents the place of hydron pellet implantation. B: Neovascularization in rat corneas after implantation bFGF hydron pellets or pellets containing bFGF and VS. The length (left panel) and area (right panel) of neovascularized vessels in rat corneas were measured after implantation for 3-7 days. Bars represent the means and the error bars represent the SEM. The asterisk indicates statistical significance (p<0.001).