Table 2 of
Kerrison, Mol Vis 2005;
11:208-215.
Table 2. Features of neurite outgrowth
The table summarizes the average normalized neurite length, neurite count, and branch point count from five experiments. For each factor, the parameter was normalized to the media alone. The p values correspond to the statistical comparisons of neurite length ratio, neurite count ratio, and branch point count made to the respective parameter for media only. While BDNF had a larger impact on neurite length and branch point count than neurite count, the BMPs tend to promote increased neurite count and branch point count to an extent comparable to their effect on neurite length (Figure 5). There were 59 wells used for each sample.
Neurite Neurite Branch length count count Treatment ratio SD p value ratio SD p value ratio SD p value --------- ------- ----- --------- ------- ----- --------- ------ ----- --------- Media 1.000 0.439 1.000 0.249 1.000 0.571 BDNF 1.874 0.627 <0.000001 1.429 0.346 <0.000001 1.896 0.808 <0.000001 BMP2 1.385 0.459 <0.000001 1.272 0.241 <0.000001 1.378 0.590 0.00058 BMP13 1.283 0.483 0.00114 1.177 0.288 0.00052 1.308 0.597 0.00493 GDF8 1.221 0.439 0.00722 1.111 0.261 0.01923 1.259 0.571 0.01524 TGFA 1.320 0.473 0.00022 1.242 0.282 <0.000001 1.160 0.554 0.12442 TGFB1 1.094 0.389 0.21966 1.056 0.273 0.24452 1.148 0.593 0.16992 TGFB2 1.041 0.460 0.62144 1.046 0.266 0.33242 1.035 0.648 0.75302 |