Table 2 of
Kerrison, Mol Vis 2005;
11:208-215.
Table 2. Features of neurite outgrowth
The table summarizes the average normalized neurite length, neurite count, and branch point count from five experiments. For each factor, the parameter was normalized to the media alone. The p values correspond to the statistical comparisons of neurite length ratio, neurite count ratio, and branch point count made to the respective parameter for media only. While BDNF had a larger impact on neurite length and branch point count than neurite count, the BMPs tend to promote increased neurite count and branch point count to an extent comparable to their effect on neurite length (Figure 5). There were 59 wells used for each sample.
Neurite Neurite Branch
length count count
Treatment ratio SD p value ratio SD p value ratio SD p value
--------- ------- ----- --------- ------- ----- --------- ------ ----- ---------
Media 1.000 0.439 1.000 0.249 1.000 0.571
BDNF 1.874 0.627 <0.000001 1.429 0.346 <0.000001 1.896 0.808 <0.000001
BMP2 1.385 0.459 <0.000001 1.272 0.241 <0.000001 1.378 0.590 0.00058
BMP13 1.283 0.483 0.00114 1.177 0.288 0.00052 1.308 0.597 0.00493
GDF8 1.221 0.439 0.00722 1.111 0.261 0.01923 1.259 0.571 0.01524
TGFA 1.320 0.473 0.00022 1.242 0.282 <0.000001 1.160 0.554 0.12442
TGFB1 1.094 0.389 0.21966 1.056 0.273 0.24452 1.148 0.593 0.16992
TGFB2 1.041 0.460 0.62144 1.046 0.266 0.33242 1.035 0.648 0.75302
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