Figure 7 of
Kerrison, Mol Vis 2005;
Figure 7. Combinatorial effects of BMP and BDNF on outgrowth neuron survival
To look for synergistic effects of BDNF with the BMPs, cultures were analyzed following addition of each BMP in the presence of BDNF at 50 ng/ml. Although an increased number of outgrowth neurons was observed in the presence of both factors relative to controls lacking growth factors, the overall effect did not exceed that of BDNF alone. The outgrowth count ratio is the number of outgrowth neurons (neurons with neurites) normalized to the number of outgrowth neurons in media only. Statistical comparisons are made to control wells without growth factors. Asterisk (*) denotes p<0.05; double asterisks (**) denote p<0.0001.