Figure 6. Dosage effect on survival of outgrowth neurons

In two experiments, cells were cultured in the presence of 0, 10, or 50 ng/ml demonstrating a positive dose response relationship for BDNF and the BMPs. Statistical comparisons are made to control wells without growth factors. For statistical comparisons to media only, an asterisk (*) denotes p<0.002; double asterisks (**) denote p<0.0001. The outgrowth count ratio is the number of outgrowth neurons (neurons with neurites) normalized to the number of outgrowth neurons in media only.