Figure 4. Quantitation of BrdU labeled corneal epithelial cells of bitransgenic and single transgenic mice

BrdU labeled corneal epithelial cells significantly increased in Kr/tet-O-FGF7 bitransgenic mice at 36 and 48 h after a single intraperitoneal injection of doxycycline compared to untreated bitransgenic mice or single transgenic mice (tet-O-FGF7 or Kr). BrdU labeling returned to baseline 72 h after a single intraperitoneal injection of doxycyline. Asterisks (*) indicate a statistically significant difference (p<0.01, unpaired t-test) for the indicated comparison.