Figure 1. Fundus pictures of rd12 homozygotes and normal C57BL/6J mice

There was no apparent fundus change in 3 month old rd12 homozygotes (A) by ophthalmoscopic examination. Small, evenly spaced white dots throughout the retina became apparent by 5 months of age (B). These dots were still detectable in 7 month old (C) and 15 month old (D) rd12 mice. No similar dots could be detected in fundi of C57BL/6J mice at 3 months (E) or 15 months (F).