Figure 2 of
Shimauchi-Matsukawa, Mol Vis 2005;
11:1220-1228.Figure 2 of
Shimauchi-Matsukawa, Mol Vis 2005;
11:1220-1228.
Figure 2. The deduced amino acid sequence of carp GRK7
Identical amino acids are shown by red letters. Blue line shows the catalytic domain of GRK1, turquoise shows the Gly loop, "GXGXXGX", and green indicates the "CaaX" motif [4].
Bovine GRK7 1 MVDMGGLDNLIANTAYLQARKSSDADSKELQRRRRSLMLPGPQSCEQLRQALATDFHSLCEQQPIGRRLFRDFLAT-VPAYQEARGFLEEVQSWELAEEG 99
Fugu GRK7-1 1 MCDMGGLDNLVANTAYL---KAQGGDDKEMKKRRRSLSLPKPDQCAAARTAIEKDFTSICERQPIGKKFFRDFLATKA-EYKVAADFLDDLYDWDLAEQA 96
Carp GRK7-1a 1 MCDMGGLDNLVANTAYL---KAQGGDDKEMKKRRRSLSLPKPEQCAALRSTLDKDFESLCEKQPIGKRFFRQYLDQGGPECNAAAEFLDDLNDWELSEAA 97
Carp GRK7-1b 1 MCDMGGLDNLVANTAYL---KAQGGDDKEMKKRRRSLSLPKTDQCVEVRSCLEKDFDSLCEKQPIGKKLFRNYLEQAGPECNAAAEFLDDLIDWELSEAA 97
Fugu GRK7-2 1 ----MGTLQGELMYLNNLVVNTTYPGAQQAGTSRSSMSLPRPKSSGLL-GSEGSCYESLCEQQPIGRRLFRQFLLDSNSQYAAAAKLLEDFDYWQHMEDE 95
-----------
Bovine GRK7 100 PAKGSALQGLVTTCAAAPVPGRPHPFFSPALVTKCQAATTDDDRASLVELAKAEVMAFLQDQPFREFLASPFYDKFLQWKVFEMQPVSDKYFEEFRVLGK 199
Fugu GRK7-1 97 -AKTKACQNIMQTYCKAD-SKKFLSFLSGEAAEKCKGVTEGNFEEVMKGKVQDGVREFLKDKPFTEFQTSPFFDKFLQWKEYEKQPISDKYFYEFRTLGK 194
Carp GRK7-1a 98 -AKDKARTNIINKFCKDG-SKSSLTFLTGDVATKCKAVTDKDFEEVM-GQVKEATKEFLKGKPFTDYQTSEFFEKFLQWKEYEKQPITEKYFYEFRTLGK 194
Carp GRK7-1b 98 -AKDKARTNIINKFCKDG-SKSSLTFLTGDVAAKCKAVTDKDFEEVM-GQVKEATKEFLKGKPFTEYQTSEFFDKFLQWKEYERQPITEKYFYEFRTLGK 194
Fugu GRK7-2 96 -AKEKAKMSVLAKFCQPE-SRTFLFSHAGDAAEKYASLSISNFDEAAMEHVREATRTFLKGGPFSEYLKSPFFYRFLQWKEYEKQKITRKYFYEFRTLGR 193
GX
----------------------------------------------------------------------------------------------------
Bovine GRK7 200 GGFGEVCAVQVKNTGKMYACKKLDKKRLKKKNGEKMALLEKEILERVSSPFIVSLAYAFESKSHLCLVMSLMNGGDLKFHIYSVG------EPGLDMSRV 293
Fugu GRK7-1 195 GGFGEVCAVQVKNTGQMYACKKLCKKRLKKKGGEKMALLEKKILEKVNSLFLVNLAYAYHTKDSLCLVMTLMNGGDLKYHIYNIGYDGKGVDKGIEMKRV 294
Carp GRK7-1a 195 GGFGEVCAVQVKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILEKVNSLFIVSLAYAYDTKTHLCLVMSLMNGGDLKYHIYNIG------EKGIEMERI 288
Carp GRK7-1b 195 GGFGEVCAVQVKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILEKVNSLFIVSLAYAYDTKTHLCLTMSLMNGGDLKYHIYNIG------EKGIEMNRI 288
Fugu GRK7-2 194 GGFGEVCAVQVKHTGQMYACKKLDKRRLKTKGGERLALIEKQILEKANSRFVINLAYAYEDRTHLCLVIDLMSGGDLKFHIYDLG------KRGIRMERV 287
GXXG
----------------------------------------------------------------------------------------------------
Bovine GRK7 294 IFYSAQITCGVLHLHSLGIVYRDMKPENVLLDDLGNCRLSDLGLAVQIQDGKPITQRAGTNGYMAPEILMEKASYSYPVDWFAMGCSIYEMVAGRTPFR- 392
Fugu GRK7-1 295 VHYTAQITTGILHLHEMDIVYRDMKPENVLLDSQGQCRLSDLGLAIEIASGKTVTQMAGTGAYMAPELLSK-TPYRTSVDWWALGCSIYEMVAGYTPFKG 393
Carp GRK7-1a 289 IYYTAQITTGMLQLHNMDIVYRDMKPENVLLDSQGQCRLSDLGLAVEIPVGKTTTQKAGTGAYMAPEILTE-TPYRTSVDWWALGCSIYEMVAGYTPFKG 387
Carp GRK7-1b 289 IYYTAQIATGILHLHTMDIVYRDMKPENVLLDSQGQCRLSDLGLAVEVPVGKTITQKAGTGAYMAPEILNE-TPYRTSVDWWALGCSIYEMVAGYTPFKG 387
Fugu GRK7-2 288 VYYVAQITSGILHLHSMDIVYRDMKPENVLLDAKGQCRLSDFGLAVELPKGKKICQKAGTTGYMAPEILRQ-ENYGMSVDWWSVGCSIYEMVAARLPFK- 385
--------------------------------------------------------------------------------
Bovine GRK7 393 --DYKEKVSKEDLKQRTLKEEVRFQHSNFTEEAKDICRLFLAKTPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLVEPPFVPDPSVVYAKDINEIDDFS 490
Fugu GRK7-1 394 PESKKEKVEKEEVQRRILNEEPKWEHKFFDAVTKDIIQQFLKKKIEERLGMKNNLEDPRKHEWFKSISFPRLEAGLVDPPWTPKPNVVYAKDTGDIAEFS 493
Carp GRK7-1a 388 PEAKKEKVEKEEVQRRIINEEPKFEHKNFNAPTIDIIKQFLKKKIDERLGCKG--DDPRKHEWFKSINFARLEAGLIDPPWVPKPNVVYAKDTGDIAEFS 485
Carp GRK7-1b 388 PEAKKEKVEKEEVQRRIINEEPKFEHKNFDAPTIDIIKQFLKKKIDERLGCKG--DDPRKHEWFKSINFARLEAGLIDPPWVPKPNVVYAKDTGDIAEFS 485
Fugu GRK7-2 386 --DFKEKVQNEEVTRRTLEDDCKFQHSDFDAPVKDLISHFLKKKVQNRLGCRA----STSTVW---------RRGSRSPPWVPKPNVIYAKDMDAFRTAS 470
Bovine GRK7 491 EVRGVEFDDNDKQFFQRFATGAVPIAWQEEIIETGPFAELNDPNRPAGCG--EGSSRSGVCLLL 552
Fugu GRK7-1 494 EIKGIEFDAKDDKFFKDFSTGAVAIAWQQEMIDTGLFDELNDPNRKEGGGDPDDGKKSGTCIVL 557
Carp GRK7-1a 486 EIKGIEFDAKDEKFFKEFSTGAVSIAWQKEMIDTGLFDELNDPNRKESSGGLDDDKKSGTCTLL 546
Carp GRK7-1b 486 EIKGIEFDAKDEKFFKEFSTGAVTIAWQKEMIDTGLFDELSDPNRKESCAGLDDDKKSGTCTLL 549
Fugu GRK7-2 471 EVEDVKLDSKDERFFKEFSTGAVPVRWQKEMIESGTFDLLNSSELNASCQESVCFSRM--CIIT 532
CaaX
|