Table 2 of Metzelaar-Blok, Mol Vis 2005; 11:1166-1172.


Table 2. Distribution of HLA-DR and HLA-DQ antigens in uveal melanoma patients and healthy Dutch blood donors

The "p corrected" column represents the correction of p values for the number of comparisons (93) conducted according to the method of Edwards [35]. The asterisk (*) indicates that the number of healthy individuals typed for this specific allele is fewer than 2,440.

               Uveal melanoma           Dutch blood
              patients (n=159)       donors (n=2440)
             -------------------   -------------------
              Number    Percent     Number    Percent    Odds         p            p
HLA allele   positive   positive   positive   positive   Ratio   uncorrected   corrected
----------   --------   --------   --------   --------   -----   -----------   ---------
DR1             24         15        473          20     0.734     0.1782       1.0000
DR3             46         29        599          25     1.228     0.2995       1.0000
DR4             44         28        679          28     0.974     0.9276       1.0000
DR7             33         21        459          19     1.117     0.6044       1.0000
DR8             13          8        128           5     1.624     0.1483       1.0000
DR10             4          3        100           4     0.661     0.4074       1.0000
DR11 (DR5)      21         13        340          14     0.937     0.8145       1.0000
DR12 (DR5)       5          3        108           5     0.743     0.5508       1.0000
DR13 (DR6)      48         30        669          28     1.096     0.6502       1.0000
DR14 (DR6)       9          6        127           5     1.094     0.8566       1.0000
DR15 (DR2)      47         30        414*         26     1.231     0.2964       1.0000
DR16 (DR2)       3          2         43           2     1.177     1.0000       1.0000
DQ2             64         40        881        1479     1.134     0.4985       1.0000
DQ4             12          8         29*          3     2.547     0.0129       0.6856
DQ5 (DQ1)       39         25        300*         35     0.619     0.0132       0.6945
DQ6 (DQ1)       83         52        453*         50     1.087     0.6674       1.0000
DQ7 (DQ3)       40         25        652          28     0.877     0.5216       1.0000
DQ8 (DQ3)       27         17        184*         20     0.817     0.3882       1.0000
DQ9 (DQ3)       14          9         71*          8     1.177     0.6340       1.0000

Metzelaar-Blok, Mol Vis 2005; 11:1166-1172 <http://www.molvis.org/molvis/v11/a134/>
©2005 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535