Table 2 of
Metzelaar-Blok, Mol Vis 2005;
11:1166-1172.
Table 2. Distribution of HLA-DR and HLA-DQ antigens in uveal melanoma patients and healthy Dutch blood donors
The "p corrected" column represents the correction of p values for the number of comparisons (93) conducted according to the method of Edwards [35]. The asterisk (*) indicates that the number of healthy individuals typed for this specific allele is fewer than 2,440.
Uveal melanoma Dutch blood patients (n=159) donors (n=2440) ------------------- ------------------- Number Percent Number Percent Odds p p HLA allele positive positive positive positive Ratio uncorrected corrected ---------- -------- -------- -------- -------- ----- ----------- --------- DR1 24 15 473 20 0.734 0.1782 1.0000 DR3 46 29 599 25 1.228 0.2995 1.0000 DR4 44 28 679 28 0.974 0.9276 1.0000 DR7 33 21 459 19 1.117 0.6044 1.0000 DR8 13 8 128 5 1.624 0.1483 1.0000 DR10 4 3 100 4 0.661 0.4074 1.0000 DR11 (DR5) 21 13 340 14 0.937 0.8145 1.0000 DR12 (DR5) 5 3 108 5 0.743 0.5508 1.0000 DR13 (DR6) 48 30 669 28 1.096 0.6502 1.0000 DR14 (DR6) 9 6 127 5 1.094 0.8566 1.0000 DR15 (DR2) 47 30 414* 26 1.231 0.2964 1.0000 DR16 (DR2) 3 2 43 2 1.177 1.0000 1.0000 DQ2 64 40 881 1479 1.134 0.4985 1.0000 DQ4 12 8 29* 3 2.547 0.0129 0.6856 DQ5 (DQ1) 39 25 300* 35 0.619 0.0132 0.6945 DQ6 (DQ1) 83 52 453* 50 1.087 0.6674 1.0000 DQ7 (DQ3) 40 25 652 28 0.877 0.5216 1.0000 DQ8 (DQ3) 27 17 184* 20 0.817 0.3882 1.0000 DQ9 (DQ3) 14 9 71* 8 1.177 0.6340 1.0000 |