Figure 8. Pathway analysis of Dex modulated genes by EASE

EASE was used to analyze genes that were modulated with dexamethasone and vehicle treatment. The total number of genes in each pathway is indicated next to the pie slice which represents the relative number of genes with modulated expression in the pathway. Some genes may be represented in more than one pathway. Not all of the genes are classified and thus do not fall into one of the pathways represented here. Of the 215 modulated transcripts, 41 were classified. Pathway analysis by EASE reveals that Dex modulated genes play a role in important signaling pathways. Dex modulated genes may be coordinately working together to modulate a signaling pathway.