Table 1 of
Melki, Mol Vis 2005;
11:1012-1017.Table 1 of
Melki, Mol Vis 2005;
11:1012-1017.
Table 1. Allele frequencies of CYP1B1 SNPs in 224 POAG patients and 47 controls
Six common variants were genotyped in the CYP1B1 gene, one (2805T>C) in the promoter region and the other five in the coding region. They show similar allele frequencies in patients and in controls. The first allele and the position correspond to the consensus sequence (CYP1B1 EMBL/Genbank: U56438). Except for the 2805 position, the variant allele is the minor one.
Sample sizes (%)
Nucleotide ----------------------
Variant change Patients Controls
------- ---------- ---------- ---------
2805T>C 2805T>C 340 (75.9) 74 (78.7)
R48G 3947C>G 112 (25) 21 (22.3)
A119S 4160G>T 122 (27.2) 21 (22.3)
L432V 8131C>G 202 (45.1) 39 (41.5)
D449D 8184C>T 194 (43.3) 38 (40.4)
N453S 8195A>G 98 (21.9) 22 (23.4)
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