Table 3 of
Otteson, Mol Vis 2005;
11:986-995.Table 3 of
Otteson, Mol Vis 2005;
11:986-995.
Table 3. Comparisons of crx sequences by exon across species (percent identity)
Cross-species sequence comparisons of Crx. The three identified exons in zebrafish Crx share sequence identity with all the four identified exons in the mammalian CRX genes. A: Zebrafish Crx Exon 1 shares a region of moderate sequence identity with human, mouse and dog Crx Exon 1 in the non-coding, 5' untranslated region. B: A second region of zebrafish Crx Exon 1 shares slightly higher sequence identity with human, mouse and dog Crx Exon 2. This slight increase in sequence identity is attributable to the high sequence identity within the coding regions. C: The coding regions in Zebrafish Crx Exon 2 and the mammalian Exon 3 and zebrafish Exon 3 and the mammalian Exon 4 share the highest sequence identity. D: The lowest level of identity is in the non-coding, 3' untranslated regions of zebrafish Crx exon 3 and the mammalian CRX exon 4. These comparisons used sequences from zebrafish ("Z"; Danio rerio; AF0503443); human ("H"; Homo sapiens; BC016664, BG396702); mouse ("M"; Mus musculus; AK053533); dog ("D"; Canis familiaris; AF454668).
A. 5' UTR (non-coding)
Z EXON 1 H EXON 1 M EXON 1 D EXON 1
-------- -------- -------- -------- --------
Z EXON 1 100 55.5 47.6 49.3
H EXON 1 100.0 69.2 66.2
M EXON 1 100.0 60.0
B. 5' UTR + Coding
Z EXON 1 H EXON 2 M EXON 2 D EXON 2
-------- -------- -------- -------- --------
Z EXON 1 100.0 56.0 57.1 55.6
H EXON 2 100.0 84.4 87.6
M EXON 2 100.0 75.5
C. Coding
Z EXON 2 H EXON 3 M EXON 3 D EXON 3
-------- -------- -------- -------- --------
Z EXON 2 100.0 74.3 69.7 73.0
H EXON 3 100.0 90.8 88.2
M EXON 3 100.0 88.9
Z EXON 3 H EXON 4 M EXON 4 D EXON 4
-------- -------- -------- -------- --------
Z EXON 3 100.0 56.4 53.0 57.2
H EXON 4 100.0 87.0 88.8
M EXON 4 100.0 84.7
D. 3' UTR (non-coding)
Z EXON 3 H EXON 4 M EXON 4 D EXON 4
-------- -------- -------- -------- --------
Z EXON 3 100.0 41.6 33.6 42.5
H EXON 4 100.0 44.9 48.1
M EXON 4 100.0 45.6
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