Table 2 of
Zhang, Mol Vis 2005;
11:977-985.
Table 2. Two-point linkage results for markers around the RP locus on chromosome 13q34
The asterisk represents the disease allele (2=111 bp) for D13S285, which was detected in four of 154 (0.026) control chromosomes. The double asterisks denote haplotype 2211 of the D13S261, D13S285, D13S1295, and D13S293 region. The incidence of one allele in 156 control chromosomes accounts for the haplotype allele frequency of 0.0064.
Position Lod score by θ --------------- ------------------------------------------------- Markers cM Mb 0.00 0.01 0.05 0.10 0.20 0.30 0.40 Zmax θmax ----------- ------ ------ ----- ----- ----- ---- ---- ---- ---- ---- ---- D13S1265 101.70 -- -1.00 -1.22 -0.01 0.35 0.48 0.38 0.21 0.48 0.18 D13S1315 105.20 108.04 -1.00 -0.67 -0.08 0.08 0.11 0.06 0.01 0.12 0.16 D13S261 112.70 109.72 2.48 2.43 2.20 1.92 1.34 0.78 0.30 2.48 0.00 D13S285 112.80 110.74 2.83 2.77 2.55 2.26 1.68 1.11 0.56 2.83 0.00 D13S1295 112.90 111.04 1.36 1.33 1.22 1.09 0.82 0.56 0.29 1.36 0.00 D13S293 117.50 112.23 0.76 0.74 0.65 0.55 0.35 0.17 0.05 0.76 0.00 D13S285* 2.89 2.83 2.60 2.31 1.72 1.13 0.56 2.89 0.00 Haplotype** 2.90 2.85 2.62 2.32 1.73 1.14 0.56 2.90 0.00 |