Table 1 of
Vazquez-Chona, Mol Vis 2005;
11:958-970.
Table 1. Data used to define acute phase genes
We performed a meta-analysis of previous experimental data to select a group of acute phase genes that are part of a common response to injury in neural tissues. Previously, we examined transcript levels in injured retina, injured brain, cultured astrocytes, and in forebrains from a panel of 35 BXD RI strains [1,6,7,9,12,17]. Microarray data sets describing transcript levels in injured spinal cord, cultured microglia, cultured neurons, and developing retina were obtained from publicly available published studies [8,18-21]. All datasets are available online at Gene Expression Omnibus (GEO).
Reactive GEO number, response Microarray Experimental website, Tissue inducer Species platform conditions or reference ---------- ------------ ------- ---------- ------------ ------------------ Injured Retinal tear Rat U34A 4 h; and 1, GSE1001 [1] retina 3, 7, & 30 d Injured Cortical Rat U34A 3 h GSE1911 [6,7] brain impact Injured Cord Rat U34A 4 h GSE464 [8] spinal contusion cord Optic Cell culture Human U95Av2 Cell culture GDS532 [17] nerve head astrocyte Cortical Cell culture Rat U34A Cell culture GSM34300 astrocyte Brain Cell culture Rat U34A Cell culture [18,19] microglia Neuron Cell culture Mouse U74Av2 Cell culture JAJohnson [20] Developing Development Mouse U74Av2 P0, P4, P8, RetDevGE [21] retina P10, P12, P14, P21, & adult Adult Genetic Mouse U74Av2 C57BL/6, [9,12] forebrain variation DBA2/J, F1, & 32 BXD RI strains |