Table 1 of Vazquez-Chona, Mol Vis 2005; 11:958-970.

Table 1. Data used to define acute phase genes

We performed a meta-analysis of previous experimental data to select a group of acute phase genes that are part of a common response to injury in neural tissues. Previously, we examined transcript levels in injured retina, injured brain, cultured astrocytes, and in forebrains from a panel of 35 BXD RI strains [1,6,7,9,12,17]. Microarray data sets describing transcript levels in injured spinal cord, cultured microglia, cultured neurons, and developing retina were obtained from publicly available published studies [8,18-21]. All datasets are available online at Gene Expression Omnibus (GEO).

               Reactive                                              GEO number,
               response               Microarray   Experimental       website,
  Tissue       inducer      Species    platform     conditions       or reference
----------   ------------   -------   ----------   ------------   ------------------
Injured      Retinal tear    Rat        U34A       4 h; and 1,    GSE1001 [1]
retina                                             3, 7, & 30 d

Injured      Cortical        Rat        U34A       3 h            GSE1911 [6,7]
brain        impact

Injured      Cord            Rat        U34A       4 h            GSE464 [8]
spinal       contusion

Optic        Cell culture    Human      U95Av2     Cell culture   GDS532 [17]
nerve head

Cortical     Cell culture    Rat        U34A       Cell culture   GSM34300

Brain        Cell culture    Rat        U34A       Cell culture   [18,19]

Neuron       Cell culture    Mouse      U74Av2     Cell culture   JAJohnson [20]

Developing   Development     Mouse      U74Av2     P0, P4, P8,    RetDevGE [21]
retina                                             P10, P12,
                                                   P14, P21,
                                                   & adult

Adult        Genetic         Mouse      U74Av2     C57BL/6,       [9,12]
forebrain    variation                             DBA2/J, F1,
                                                   & 32 BXD
                                                   RI strains

Vazquez-Chona, Mol Vis 2005; 11:958-970 <>
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ISSN 1090-0535