Table 4 of
Schmidt, Mol Vis 2005;
11:941-949.Table 4 of
Schmidt, Mol Vis 2005;
11:941-949.
Table 4. APOE genotype-specific effects of smoking history on risk of AMD (grade 3-5)
Odds ratios (OR) and p values were derived from a logistic regression model in which the variables were coded as described in the Methods section of the text. They were adjusted for age and sex. APOE genotypes 2/2, 2/3, and 2/4 were combined into the 2/* category. APOE genotypes 4/2, 4/3, 4/4 genotypes were combined into the 4/* category. Thus, APOE-2/4 genotypes were included in both of these categories (5 cases, 4 controls).
APOE genotype Smoking Cases Controls OR 95% CI p value -------- ------- ----- -------- --------- --------- ------- 3/3 Never 93 64 1.0 (ref) 2/* Never 27 13 1.4 0.5 - 3.9 0.48 4/* Never 25 29 0.7 0.2 - 1.5 0.34 3/3 Ever 148 64 1.8 1.1 - 3.0 0.02 2/* Ever 41 10 3.0 1.3 - 7.2 0.01 4/* Ever 48 22 1.6 0.8 - 3.1 0.20 |