Table 1 of
Schmidt, Mol Vis 2005;
11:941-949.Table 1 of
Schmidt, Mol Vis 2005;
11:941-949.
Table 1. Clinical description of the study population
The clinical classification of 377 AMD patients and 198 unaffected controls is shown in the table. The grading system is taken from Schmidt et al. [19] and Seddon et al. [27]. Population characteristics are shown in the lower table. RPE represents retinal pigment epithelium.
Clinical description AMD grade Cases (%) Controls (%) -------------------------------- --------- ----------- ------------ No drusen or small (<63 μm) 1 136 (68.7) nonextensive drusen without RPE abnormalities Extensive small drusen or 2 62 (31.3) nonextensive intermediate drusen (>=63 μm and <125 μm) and/or RPE hyper- or hypopigmentation Extensive intermediate drusen or 3 76 (20.2) any large (>=125 μm), soft drusen, including drusenoid RPE detachment Geographic atrophy (area of RPE 4 41 (10.9) atrophy with sharp margins, usually visible choroidal vessels, at least 175 μm diameter) Exudative AMD, including 5 260 (68.9) nondrusenoid RPE detachment, choroidal neovascularization, subretinal hemorrhage or fibrosis, or photocoagulation scar consistent with treatment of AMD -------------------------------- --------- ----------- ------------ Total 377 198 |
Population characteristics Cases Controls ---------------------------- ---------- ---------- Female (%) 240 (63.7) 123 (62.1) Mean age at examination (SD) 75.9 (7.7) 66.8 (7.7) |