Table 1 of
Ramprasad, Mol Vis 2005;
11:934-940.Table 1 of
Ramprasad, Mol Vis 2005;
11:934-940.
Table 1. Clincial features of all the affected individuals of the MCOR pedigree
All individuals listed displayed microcoria. The table details clinical data for the pedigree individuals relevant to the diagnosis of myopia (refractive error and axial length, where available) and glaucoma (intraocular pressure [IOP], cup/disc ratio, and visual field status). It was not possible (NP) to assess the IOP and/or the cup to disc ratio in some eyes. Some data were not available (NA) in all patients. A cup to disc ratio was not estimated in eyes with glaucomatous optic atrophy (GOA). Patients using ocular hypotensive agents are indicated with an asterisk.
IOP Cup/disc
ID Age, Refractive (mm Hg; ratio Humphrey
number sex error OD, OS) (OD, OS) visual fields Comments
------ ----- ---------- ------- -------- ------------- ----------------------
Z19 45, M Emmetrope 19,21 0.3, 0.3 Normal Axial length: 22.46
mm (OD), 22.76 mm (OS)
Z21 55, M Myopia 12 GOA NA Bilaterally blind
(light perception
vision), corneal
decompensation (OS),
historically had
myopic corrections
Z22 65, M Myopia 18,16 NP NA
(-2.0 D)
Z23 40, M Myopia NP NP NA Bilaterally blind
(perception of light
vision), after
trabeculectomy both
eyes. Historically had
myopic corrections
Z28 23, F Myopia 18,16 0.2, 0.3 NA
(-1.0 D)
Z30 12, M Myopia 29,43 0.3, GOA NA Axial length: 23.57
(-3.0 D, mm (OD), 25.62 mm (OS)
-3.5 D)
Z31 16, F Myopia 14,14 0.4 (OU) NA
(-2.0 D)
Z33 24, M Myopia 13,14 GOA, 0.4 Biarcuate Post trabeculectomy
(-22.0 D) defect (OS) (OU)
Z35 25, F Myopia 18,18* 0.2 (OU) Normal Baseline IOP: 35 mm Hg
(-8.0 D)
Z36 15, F Myopia 13,15 0.2, 0.3 NA
(-1.0 D)
Z37 16, F Emmetropia 18,18 0.3 (OU) NA
Z38 5, F Emmetropia NA NA NA
S58 17, M Myopia 33,26* 0.6, 0.4 Generalized Index Case
(-17.0 D, reduction of
-18.0 D) sensitivity
W51 33, M Myopia 32,19* 0.8, 0.6 Nasal step
(-12.5 D) (OD),
generalized
reduction of
sensitivity
(OS)
K1-46 35, M Myopia 25,17* 0.6, 0.2 Superior Axial length: 22.95
(-3.28 D) arcuate (OD), mm (OD), 22.96 mm (OS)
nasal defects
(OS)
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