Table 3 of
Wegscheider, Mol Vis 2005;
11:896-900.Table 3 of
Wegscheider, Mol Vis 2005;
11:896-900.
Table 3. Genotype frequencies in cases and HLA-B27 controls
This table shows the CCL2 -2518 genotype distribution in patients and control groups. Genotype distribution of the CCL2 -2518A>G polymorphism did not significantly differ between patients and healthy HLA-B27 negative control subjects (p=0.97). Carriers of a CCL2 -2518G allele were found significantly more often in HLA-B27 positive patients than in HLA-B27 positive controls (OR=2.1, 95% CI 1.2-3.6; p=0.007).
Controls
HLA-B27 ---------------------
associated HLA-B27 HLA-B27
AAU patients negative positive
Genotype (n=114) (n=88) (n=111)
------------------ ------------ --------- ---------
CCL2 -2518AA 58 (50.9) 45 (51.1) 76 (68.5)
CCL2 -2518AG 46 (40.4) 38 (43.3) 31 (27.9)
CCL2 -2518GG 10 (8.8) 5 (5.7) 4 (3.6)
CCL2 -2518G 0.29 0.27 0.18
allele frequency
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