Table 3 of Wegscheider, Mol Vis 2005; 11:896-900.


Table 3. Genotype frequencies in cases and HLA-B27 controls

This table shows the CCL2 -2518 genotype distribution in patients and control groups. Genotype distribution of the CCL2 -2518A>G polymorphism did not significantly differ between patients and healthy HLA-B27 negative control subjects (p=0.97). Carriers of a CCL2 -2518G allele were found significantly more often in HLA-B27 positive patients than in HLA-B27 positive controls (OR=2.1, 95% CI 1.2-3.6; p=0.007).

                                          Controls
                       HLA-B27      ---------------------
                      associated     HLA-B27     HLA-B27
                     AAU patients   negative    positive
     Genotype          (n=114)       (n=88)      (n=111)
------------------   ------------   ---------   ---------
CCL2 -2518AA          58 (50.9)     45 (51.1)   76 (68.5)
CCL2 -2518AG          46 (40.4)     38 (43.3)   31 (27.9)
CCL2 -2518GG          10  (8.8)      5  (5.7)    4  (3.6)

CCL2 -2518G            0.29          0.27        0.18
  allele frequency

Wegscheider, Mol Vis 2005; 11:896-900 <http://www.molvis.org/molvis/v11/a106/>
©2005 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535