Figure 1. A dendrogram and chromosomal locations of the SLRP genes

The dendrogram shows relationships between SLRP family members in the human and mouse genomes. Based on their chromosomal organization, overall protein structure, and the structure of cysteine rich clusters in their N terminus they are subdivided into four classes. ECM2 is not a SLRP, but has a lucine rich repeat (LRR) domain and is physically linked to a SLRP cluster on chromosome 9. This analysis was done using GenWorks version 2.5 (IntelliGenetics, Inc. Oxford).