Table 1 of Nakamura, Mol Vis 2004; 10:703-711.


Table 1. Target and duplex sequences for TβRII specific siRNAs

Four siRNAs, designated as hT1, hT2, hT3, and hT4, were designed from the coding sequence of the human TβRII gene. The target sequences (5'-3') and the siRNA duplex sequences are listed, with the position of the first nucleotide in the human TβRII sequence shown in parentheses. siRNA from the similar region as hT1 of the mouse TβRII sequence was also designed and the target sequence of the mouse T1 (mT1) siRNA is shown. There is one nucleotide difference (small letter) between the human and mouse TβRII sequences.

siRNA
duplex   Species     TβRII sequence (5'-3')       siRNA duplex sequences
------   -------   ---------------------------   -------------------------
 hT1      Human     (529)AATCCTGCATGAGCAACTGCA   5'UCCUGCAUGAGCAACUGCAdTdT
                                                 dTdTAGGACGUACUCGUUGACGU

 hT2      Human    (1253)AGCATGAGAACATACTCCAG    5'GCAUGAGAACAUACUCCAGdTdT
                                                 dTdTCGUACUCUUGUAUGAGGUC

 hT3      Human    (1113)AAGGCCAAGCTGAAGCAGAAC   5'GGCCAAGCUGAAGCAGAACdTdT
                                                 dTdTCCGGUUCGACUUCGUCUUG

 hT4      Human     (948)AAGACGCGGAAGCTCATGGAG   5'GACGCGGAAGCUCAUGGAGdTdT
                                                 dTdTCUGCGCCUUCGAGUACCUC

 mT1      Mouse     (195)AgTCCTGCATGAGCAACTGCA   5'UCCUGCAUGAGCAACUGCAdTdT
                                                 dTdCAGGACGUACUCGUUGACGU

Nakamura, Mol Vis 2004; 10:703-711 <http://www.molvis.org/molvis/v10/a85/>
©2004 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535