Table 2 of
Hackam, Mol Vis 2004;
10:637-649.
Table 2. Functional annotation of the top 30 retina enriched genes
The top thirty genes shared between retina-brain and retina-liver comparisons are listed, along with their corresponding Unigene cluster numbers and expression ratios and function.
Gene Unigene Retina/brain Retina/liver Function
-------------------------------- --------- ------------ ------------ ------------------------
phosducin Mm.1205 22.818 56.996 signal, visual system
rhodopsin Mm.2965 12.95 55.155 signal, visual system
heat shock protein 60 kDa Mm.1777 6.084 35.004 heat shock
guanine nucleotide binding Mm.2344 5.558 27.5 signal, visual system
protein beta 1
retinal S antigen Mm.1276 4.99 17.557 signal, visual system
neural retina leucine zipper Mm.20422 4.685 7.382 DNA, visual system
crystallin alpha 1 Mm.1228 4.119 9.217 chaperone, visual system
aryl hydrocarbon interacting Mm.95707 3.752 5.876 transport, visual system
protein like 1
TPA regulated locus Mm.790 3.557 6.895 unknown function
EST Mm.293263 3.526 7.165 EST
IMAGE 4511806 Mm.194050 3.02 8.323 EST
retinaldehyde binding protein 1 Mm.41653 2.635 5.318 unknown function, visual
system
RAB10 member RAS oncogene family Mm.74596 2.632 5.421 signal
IMAGE 4505626 (RIRD1; ref5) Mm.276787 2.519 2.041 EST
alpha enolase Mm.327368 2.39 4.025 metabolism
homeodomain protein CRX Mm.8008 2.344 2.269 nucleic, visual system
guanylate cyclase activator 1a Mm.16224 2.33 2.088 signal, visual system
retina
erythrocyte protein band 4 Mm.30038 2.289 2.372 transport, structure
RNA polymerase II Mm.41746 2.271 5.095 nucleic acid
transcriptional coactivator
ELOVL4 Mm.83949 2.252 3.708 unknown function
retinol binding protein 3 Mm.151562 2.226 2.674 transport, visual system
mouse homolog of hnRNP 2H9B Hs.156481 2.189 4.217 RNA
H3 histone family 3B Mm.18516 2.126 3.142 nucleic acid
mouse homolog of CGI Hs.5298 2.099 2.051 unknown
45/adiponectin receptor 1
Ras homolog gene family, Mm.261491 2.016 3.512 EST
member T1
X linked juvenile retinoschisis Mm.41982 2.005 2.462 structure
protein
prominin Mm.6250 2.004 2.353 unknown
solute carrier family 6 (taurine) Mm.200518 1.951 3.133 transport
EST Mm.32460 1.933 2.399 EST
EST similar to Pyruvate kinase 3 Mm.2635 1.916 8.524 metabolism
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