Table 2 of
Hackam, Mol Vis 2004;
10:637-649.
Table 2. Functional annotation of the top 30 retina enriched genes
The top thirty genes shared between retina-brain and retina-liver comparisons are listed, along with their corresponding Unigene cluster numbers and expression ratios and function.
Gene Unigene Retina/brain Retina/liver Function -------------------------------- --------- ------------ ------------ ------------------------ phosducin Mm.1205 22.818 56.996 signal, visual system rhodopsin Mm.2965 12.95 55.155 signal, visual system heat shock protein 60 kDa Mm.1777 6.084 35.004 heat shock guanine nucleotide binding Mm.2344 5.558 27.5 signal, visual system protein beta 1 retinal S antigen Mm.1276 4.99 17.557 signal, visual system neural retina leucine zipper Mm.20422 4.685 7.382 DNA, visual system crystallin alpha 1 Mm.1228 4.119 9.217 chaperone, visual system aryl hydrocarbon interacting Mm.95707 3.752 5.876 transport, visual system protein like 1 TPA regulated locus Mm.790 3.557 6.895 unknown function EST Mm.293263 3.526 7.165 EST IMAGE 4511806 Mm.194050 3.02 8.323 EST retinaldehyde binding protein 1 Mm.41653 2.635 5.318 unknown function, visual system RAB10 member RAS oncogene family Mm.74596 2.632 5.421 signal IMAGE 4505626 (RIRD1; ref5) Mm.276787 2.519 2.041 EST alpha enolase Mm.327368 2.39 4.025 metabolism homeodomain protein CRX Mm.8008 2.344 2.269 nucleic, visual system guanylate cyclase activator 1a Mm.16224 2.33 2.088 signal, visual system retina erythrocyte protein band 4 Mm.30038 2.289 2.372 transport, structure RNA polymerase II Mm.41746 2.271 5.095 nucleic acid transcriptional coactivator ELOVL4 Mm.83949 2.252 3.708 unknown function retinol binding protein 3 Mm.151562 2.226 2.674 transport, visual system mouse homolog of hnRNP 2H9B Hs.156481 2.189 4.217 RNA H3 histone family 3B Mm.18516 2.126 3.142 nucleic acid mouse homolog of CGI Hs.5298 2.099 2.051 unknown 45/adiponectin receptor 1 Ras homolog gene family, Mm.261491 2.016 3.512 EST member T1 X linked juvenile retinoschisis Mm.41982 2.005 2.462 structure protein prominin Mm.6250 2.004 2.353 unknown solute carrier family 6 (taurine) Mm.200518 1.951 3.133 transport EST Mm.32460 1.933 2.399 EST EST similar to Pyruvate kinase 3 Mm.2635 1.916 8.524 metabolism |