Table 1 of
McColm, Mol Vis 2004;
10:512-520.Table 1 of
McColm, Mol Vis 2004;
10:512-520.
Table 1. The effect of oxygen fluctuations on retinal vascularization
The table contains data from the retinal flatmount images on total retinal area, radial extent of vascularization, weights of the animals and the clock hours of pathological neovascularization for the different time points in controls and OIR animals. Values are means, and the standard deviation is given in parentheses below each mean, except where otherwise stated. Each time point of control or OIR animals is the combined data from 12 animals, 96 animals in total. Whole body weight refers to the weight of the animal at the end of the experiment.
Avascular Clock hours of
periphery Rat neovascularization
Total retinal (% of total whole body (median/interquartile
area (sq. mm) retinal area) weight (g) range)
Postnatal ------------- ------------- ------------- ---------------------
age (days) RA 50/10 RA 50/10 RA 50/10 RA 50/10
---------- ----- ----- ----- ----- ----- ----- ------ ------------
2 26.5 20.6 61.1 82.8 9.3 6.3 0 0
(1.0) (1.9) (5.0) (2.9) (0.2) (0.4)
7 31.6 27.2 24.3 51.2 10.9 7.5 0 0
(1.1) (3.0) (3.8) (5.0) (0.5) (0.3)
14 39.3 33.4 0 32.8 30.1 18.1 0 0
(0.4) (3.4) (10.6) (2.9) (1.2)
18 38.9 39.3 0 23.1 31.7 25.7 0 9.5
(1.5) (1.8) (6.2) (1.4) (1.7) (9.5-10.3)
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