Figure 8. Correlation of retinal VEGF mRNA to neovascularization severity

Correlation of retinal VEGF mRNA to neovascularization severity (clock hours) in contralateral eyes of rats in hypercarbic OIR litters on day 13 by Northern blot analysis (A) and qRT-PCR (B). Positive correlations (Spearman) were seen between retinal VEGF mRNA levels and severity of neovascularization by both techniques. NV refers to neovascularization.