Figure 6. Retinal IGF-1 mRNA expression in hypercarbic OIR

Retinal IGF-1 mRNA in hypercarbic OIR measured by Northern blot analysis (A) and qRT-PCR (B). Retinal IGF-1 mRNA was decreased by Northern blot analysis at days 8, 10, and 13 but returned to normal by day 20. Retinal IGF-1 mRNA was decreased by qRT-PCR at day 8, returned to normal by day 10, and remained unchanged from control values at days 13 and 20. P values are for comparisons of OIR and room air controls at each time. Non-significant comparisons are labelled "NS" (p>0.05).