Figure 1. A French-Canadian pedigree with one affected individual for cone-rod degeneration

Phenotype and allelic state of the family members are shown. The proband and the only affected individual is II-1. The allelic state is denoted with +/+ (wild type) and +/- (carriers of heterozygous mutation K270del). The gel underneath displays the heteroduplexes analysis that shows the K270del mutation, and its distribution in the family.