Figure 4. Transmission electron micrographs of removed lens tissue from affected individuals

A: There were foci of dense, globular deposits (0.05 to 0.5 μM in diameter) in the cytosol of the lens fiber cells, either surrounded by a single membrane (arrow) or deposited freely in the cytoplasm (arrowhead). B:The lens fiber cell borders were highly irregular and there was increased space (about 0.1 to 0.5 μM in width) between the cells (arrows).