Table 4 of
Young, Mol Vis 2004;
10:163-176.Table 4 of
Young, Mol Vis 2004;
10:163-176.
Table 4. Genes expressed in human donor sclera that map to chromosome loci with defined intervals
A description of genes expressed in human donor sclera that map to chromosome loci with defined intervals (chromosomes 18p11.31, 17q21-22, 12q23-24, and 7q36) associated with non-syndromic high-grade myopia, associated accession number, gene symbol, and cytogenetic position.
Accession Cytogenetic number Name Gene position ---------- ------------------------------ -------- --------------- NM_006788 ralA binding protein 1 RALBP1 18p11.3 NM_021074 NADH dehydrogenase NDUFV2 18p11.31-p11.2 (ubiquinone) flavoprotein 2 (24kD) NM_003803 myomesin 1 (skelemin, 185 kD) MYOM1 18p11.31-p11.32 NM_005433 v-yes-1 Yamaguchi sarcoma YES1 18p11.31-p11.21 viral oncogene homolog 1 NM_174886 TGFB-induced factor (TALE TGIF 18p11.3 family homeobox) NM_013292 myosin regulatory light chain MLC-B 18p11.31 NM_004583 Cluster Incl. U18420:Human RAB5C 17q21.2 ras-related small GTP binding protein Rab5 (rab5) mRNA, complete cds /cds=(135,785) /gb=U18420 /gi=642531 /ug=Hs.479 /len=1579 NM_001096 Cluster Incl. X64330:H.sapiens ACLY 17q12-q21 mRNA for ATP-citrate lyase /cds=(84,3401) /gb=X64330 /gi=28934 /ug=Hs.174140 /len=4297 NM_006807 Cluster Incl. U35451:Homo CBX1 17q sapiens heterochromatin protein p25 mRNA, complete cds /cds=(216,773) /gb=U35451 /gi=1177844 /ug=Hs.77254 /len=2148 NM_003488 Cluster Incl. X97335:H.sapiens AKAP1 17q21-q23 mRNA for kinase A anchor protein /cds=(124,2835) /gb=X97335 /gi=1507823 /ug=Hs.78921 /len=3758 NM_002634 Cluster Incl. PHB 17q21 S85655:prohibitin [human, mRNA, 1043 nt] /cds=(50,868) /gb=S85655 /gi=246482 /ug=Hs.75323 /len=1024 NM_006380 Cluster Incl. D86981:Human APPBP2 17q21-q23 mRNA for KIAA0228 gene, partial cds /cds=(0,2045) /gb=D86981 /gi=1504035 /ug=Hs.84084 /len=6465 NM_014233 Cluster Incl. X53390:Human UBTF 17q21.3 mRNA for upstream binding factor (hUBF) /cds=(147,2441) /gb=X53390 /gi=509240 /ug=Hs.89781 /len=3097 NM_002512 Cluster Incl. X58965:H.sapiens NME2 17q21.3 RNA for nm23-H2 gene /cds=(72,530) /gb=X58965 /gi=35069 /ug=Hs.227823 /len=670 NM_022739 Cluster Incl. SMURF2 17q22-q23 AA630312:ac08f05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-855873 /clone_end=3 /gb=AA630312 /gi=2552923 /ug=Hs.21806 /len=685 NM_025233 Cluster Incl. U18919:Human NBP 17q12-q21 chromosome 17q12-21 mRNA, clone pOV-2, partial cds /cds=(0,886) /gb=U18919 /gi=894177 /ug=Hs.74130 /len=1009 NM_000988 Cluster Incl. RPL27 17q21.1-q21.2 AA044823:zk72a10.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-488346 /clone_end=3 /gb=AA044823 /gi=1523026 /ug=Hs.111611 /len=649 NM_005749 Cluster Incl. D38305:Human TOB1 17q21 mRNA for Tob, complete cds /cds=(43,1080) /gb=D38305 /gi=1580723 /ug=Hs.178137 /len=1206 M23410 HUMPLAKO Human plakoglobin JUP 17q21 (PLAK) mRNA; complete cds. AF519531 Human interferon gamma SCYA2 17q11.2-q21.1 treatment inducible mRNA XM_290758 Cluster Incl. AB011125:Homo KIAA0553 17q21.31 sapiens mRNA for KIAA0553 protein, partial cds /cds=(0,3289) /gb=AB011125 /gi=3043629 /ug=Hs.105749 /len=5574 NM_004396 Cluster Incl. X52104:Human DDX5 17q21 mRNA for p68 protein /cds=(175,2019) /gb=X52104 /gi=35219 /ug=Hs.76053 /len=2330 NM_153490 Cluster Incl. X14640:Human KRT13 17q21-q23 mRNA for keratin 13 /cds=(42,1418) /gb=X14640 /gi=34032 /ug=Hs.74070 /len=1691 NM_005899 Cluster Incl. D30756:Human M17S2 17q21.1 mRNA for KIAA0049 gene, complete cds /cds=(140,3040) /gb=D30756 /gi=488500 /ug=Hs.233745 /len=4654 NM_006688 Cluster Incl. AF095154:Homo CRF 17q21 sapiens C1q-related factor mRNA, complete cds /cds=(13,789) /gb=AF095154 /gi=3747096 /ug=Hs.134012 /len=1284 NM_006460 Cluster Incl. AB021179:Homo HIS1 17q21.32 sapiens mRNA for HEXIM1 protein, complete cds /cds=(689,1768) /gb=AB021179 /gi=4062855 /ug=Hs.15299 /len=3597 NM_021137 Cluster Incl. M80783:Human B12 TNFAIP1 17q22-q23 protein mRNA, complete cds /cds=(153,1103) /gb=M80783 /gi=179303 /ug=Hs.76090 /len=3512 NM_004773 Cluster Incl. L40410:Homo TRIP3 17q21.1 sapiens thyroid receptor interactor (TRIP3) mRNA, 3 end of cds /cds=(0,458) /gb=L40410 /gi=703109 /ug=Hs.2210 /len=867 NM_025233 Cluster Incl. U18919:Human NBP 17q12-q21 chromosome 17q12-21 mRNA, clone pOV-2, partial cds /cds=(0,886) /gb=U18919 /gi=894177 /ug=Hs.74130 /len=1009 NM_001070 Cluster Incl. M61764:Human TUBG1 17q21 gamma-tubulin mRNA, complete cds /cds=(24,1379) /gb=M61764 /gi=183702 /ug=Hs.21635 /len=1568 AF073312 Cluster Incl. AF035811:Homo PNUTL2 17q22-q23 sapiens protein H5 (H5) mRNA, complete cds /cds=(129,1565) /gb=AF035811 /gi=2665833 /ug=Hs.155524 /len=1737 NM_170608. Cluster Incl. TCFL4 17q21.1 AW005997:wz91c01.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2566176 /clone_end=3 /gb=AW005997 /gi=5854775 /ug=Hs.78185 /len=702 NM_015294 Cluster Incl. AB020705:Homo TRIM37 17q22-q23 sapiens mRNA for KIAA0898 protein, partial cds /cds=(0,2939) /gb=AB020705 /gi=4240284 /ug=Hs.8164 /len=4111 NM_006148 Cluster Incl. X82456:H.sapiens LASP1 17q11-q21.3 MLN50 mRNA /cds=(75,860) /gb=X82456 /gi=2407912 /ug=Hs.75080 /len=3846 NM_005121 Cluster Incl. AB011165:Homo TRAP240 17q22-q23 sapiens mRNA for KIAA0593 protein, partial cds /cds=(0,2844) /gb=AB011165 /gi=3043709 /ug=Hs.11861 /len=4924 NM_004375 Cluster Incl. U79270:Human COX11 17q22 clone 23707 mRNA, partial cds /cds=(0,460) /gb=U79270 /gi=1710235 /ug=Hs.239420 /len=1255 NM_002512 H.sapiens RNA for nm23-H2 NME2 17q21.3 gene. NM_000269 Homo sapiens NM23-H1 mRNA NME1 17q21.3 NM_001552 Human insulin-like growth IGFBP4 17q12-q21.1 factor binding protein 4 (IGFBP4) mRNA, complete cds NM_002824 Cluster Incl. M24398:Human PTMS 17q12-q22 parathymosin mRNA, complete cds /cds=(300,608) /gb=M24398 /gi=339698 /ug=Hs.171814 /len=1109 NM_006373 Cluster Incl. U18009:Human VAT1 17q21 chromosome 17q21 mRNA clone LF113 /cds=(0,939) /gb=U18009 /gi=602277 /ug=Hs.157236 /len=2381 NM_003766 Cluster Incl. U17999:HSU17999 BECN1 17q21 Homo sapiens cDNA /clone=B49B32B27 /gb=U17999 /gi=602263 /ug=Hs.12272 /len=1758 NM_005831 Cluster Incl. U22897:Homo NDP52 17q21.32 sapiens nuclear domain 10 protein (ndp52) mRNA, complete cds /cds=(54,1394) /gb=U22897 /gi=984286 /ug=Hs.154230 /len=2387 NM_001991 Cluster Incl. AB002386:Human EZH1 17q21.1-q21.3 mRNA for KIAA0388 gene, complete cds /cds=(100,2343) /gb=AB002386 /gi=2224716 /ug=Hs.194669 /len=4606 NM_002126 Cluster Incl. M95585:Human HLF 17q22 hepatic leukemia factor (HLF) mRNA, complete cds /cds=(322,1209) /gb=M95585 /gi=184223 /ug=Hs.101047 /len=3865 NM_001256 Cluster Incl. CDC27 17q12-17q23.2 AA166687:zq41h05.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-632313 /clone_end=3 /gb=AA166687 /gi=1745142 /ug=Hs.172405 /len=703 NM_139276 Cluster Incl. L29277:Homo STAT3 17q21 sapiens DNA-binding protein (APRF) mRNA, complete cds /cds=(220,2532) /gb=L29277 /gi=475788 /ug=Hs.142258 /len=2787 NM_004687 Cluster Incl. AB014547:Homo MTMR4 17q22-q23 sapiens mRNA for KIAA0647 protein, partial cds /cds=(0,3051) /gb=AB014547 /gi=3327107 /ug=Hs.141727 /len=5183 NM_003563 Cluster Incl. AJ000644:Homo SPOP 17q21.32 sapiens mRNA for SPOP /cds=(157,1281) /gb=AJ000644 /gi=2695707 /ug=Hs.129951 /len=1642 NM_002276 Cluster Incl. Y00503:Human KRT19 17q21 mRNA for keratin 19 /cds=(32,1234) /gb=Y00503 /gi=34038 /ug=Hs.182265 /len=1360 NM_006924 Cluster Incl. M72709:Human SFRS1 17q21.3-q22 alternative splicing factor mRNA, complete cds /cds=UNKNOWN /gb=M72709 /gi=179073 /ug=Hs.73737 /len=1717 AB014512 Cluster Incl. AB014512:Homo PRAX-1 17q22-q23 sapiens mRNA for KIAA0612 protein, partial cds /cds=(0,5212) /gb=AB014512 /gi=3327037 /ug=Hs.112499 /len=6458 NM_003079 Cluster Incl. AF035262:Homo SMARCE1 17q21.1 sapiens BAF57 (BAF57) gene, complete cds /cds=(0,1235) /gb=AF035262 /gi=2914752 /ug=Hs.235497 /len=1236 NM_007359 Cluster Incl. X80199:H.sapiens MLN51 17q11-q21.3 MLN51 mRNA /cds=(233,1837) /gb=X80199 /gi=2385366 /ug=Hs.83422 /len=4253 LOC51096 Cluster Incl. LOC51096 17q21.33 AI140114:qa95c06.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-1694506 /clone_end=3 /gb=AI140114 /gi=3647571 /ug=Hs.6153 /len=741 NM_021078 Cluster Incl. AF029777:Homo GCN5L2 17q21 sapiens histone acetyltransferase (GCN5) mRNA, partial cds /cds=(24,2537) /gb=AF029777 /gi=3220163 /ug=Hs.101067 /len=3074 NM_005533 Human interferon-induced IFI35 17q21 leucine zipper protein (IFP35) mRNA, partial cds NM_006178 Cluster Incl. U03985:Human NSF 17q21 N-ethylmaleimide-sensitive factor mRNA, partial cds /cds=(0,2255) /gb=U03985 /gi=467976 /ug=Hs.108802 /len=2263 NM_005895 Cluster Incl. D63997:Homo GOLGA3 12q24.33 sapiens mRNA for GCP170, complete cds /cds=(269,4861) /gb=D63997 /gi=2662348 /ug=Hs.4953 /len=6640 NM_002813 Cluster Incl. PSMD9 12q24.31-q24.32 AI347155:tc04c11.x1 Homo sapiens cDNA, 3 end /clone=IMAGE-2062868 /clone_end=3 /gb=AI347155 /gi=4084361 /ug=Hs.5648 /len=750 NM_004642 Cluster Incl. AF006484:Homo CDK2AP1 12q24.31 sapiens putative oral tumor suppressor protein (doc-1) mRNA, complete cds /cds=(522,869) /gb=AF006484 /gi=2738496 /ug=Hs.3436 /len=1608 Z22555 Cluster Incl. Z22555:H.sapiens CD36L1 12q24.31 encoding CLA-1 mRNA /cds=(69,1598) /gb=Z22555 /gi=397606 /ug=Hs.180616 /len=2552 NM_023012 Cluster Incl. W26521:32g11 FLJ11021 12q24.31 Homo sapiens cDNA /gb=W26521 /gi=1307382 /ug=Hs.81648 /len=783 NM_006815 Cluster Incl. X92098:H.sapiens RNP24 12q24.31 mRNA for transmembrane protein rnp24 /cds=(27,632) /gb=X92098 /gi=1212964 /ug=Hs.75914 /len=780 NM_003565 Cluster Incl. AF045458:Homo ULK1 12q24.3 sapiens serine/threonine kinase ULK1 (ULK1) mRNA, complete cds /cds=(268,3420) /gb=AF045458 /gi=3435113 /ug=Hs.47061 /len=5211 XM_055013 Human ubiquitin mRNA, complete UBC 12q24.3 cds NM_002956 Cluster Incl. X64838:H.sapiens RSN 12q24.3 mRNA for restin /cds=(132,4415) /gb=X64838 /gi=35998 /ug=Hs.31638 /len=5857 NM_003299 HSTRA1 Human tra1 mRNA for TRA1 12q24.2-q24.3 human homologue of murine tumor rejection antigen gp96 NM_033624 Cluster Incl. AB020682:Homo FBXO21 12q24.23 sapiens mRNA for KIAA0875 protein, partial cds /cds=(0,1866) /gb=AB020682 /gi=4240238 /ug=Hs.184227 /len=4168 NM_002567 Cluster Incl. X75252:H.sapiens PBP 12q24.23 phosphatidylethanolamine binding protein mRNA /cds=(110,673) /gb=X75252 /gi=406289 /ug=Hs.80423 /len=1444 XM_034056 Cluster Incl. AB028948:Homo KIAA1025 12q24.22 sapiens mRNA for KIAA1025 protein, partial cds /cds=(0,3441) /gb=AB028948 /gi=5689386 /ug=Hs.4084 /len=6131 XM_045792 Cluster Incl. D86973:Human GCN1L1 12q24.2 mRNA for KIAA0219 gene, partial cds /cds=(0,7239) /gb=D86973 /gi=1504019 /ug=Hs.75354 /len=7819 NM_000690 Cluster Incl. X05409:Human RNA ALDH2 12q24.2 for mitochondrial aldehyde dehydrogenase I ALDH I (EC 1.2.1.3) /cds=(36,1586) /gb=X05409 /gi=28605 /ug=Hs.195432 /len=1989 NM_001002 Cluster Incl. M17885:Human RPLP0 12q24.2 acidic ribosomal phosphoprotein P0 mRNA, complete cds /cds=(77,1030) /gb=M17885 /gi=190231 /ug=Hs.73742 /len=1097 NM_004373 Cluster Incl. COX6A1 12q24.2 AI540925:PEC1.2_15_A02.r Homo sapiens cDNA, 5 end /clone_end=5 /gb=AI540925 /gi=4458298 /ug=Hs.180714 /len=777 NM_002710 Cluster Incl. X74008:H.sapiens PPP1CC 12q24.1-q24.2 mRNA for protein phosphatase 1 gamma /cds=(154,1125) /gb=X74008 /gi=402777 /ug=Hs.79081 /len=2263 AB014514 Cluster Incl. AB014514:Homo KIAA0614 12q24.13 sapiens mRNA for KIAA0614 protein, partial cds /cds=(0,4893) /gb=AB014514 /gi=3327041 /ug=Hs.7314 /len=7084 NM_006817 Cluster Incl. X94910:Homo C12orf8 12q24.13 sapiens mRNA for ERp28 protein /cds=(11,796) /gb=X94910 /gi=3413292 /ug=Hs.75841 /len=892 NM_004592 Cluster Incl. U08377:Human SFRS8 12q24.12 homolog of Drosophila splicing regulator suppressor-of-white-apricot mRNA, complete cds /cds=(120,2975) /gb=U08377 /gi=508230 /ug=Hs.84229 /len=3225 NM_006825 Cluster Incl. X69910:H.sapiens CKAP4 12q24.11 p63 mRNA for transmembrane protein /cds=(84,1889) /gb=X69910 /gi=297407 /ug=Hs.74368 /len=2898 AF387506 Cluster Incl. AB020880:Homo KIAA0156 12q24.11 sapiens mRNA for squamous cell carcinoma antigen SART-3, complete cds /cds=(19,2910) /gb=AB020880 /gi=4996281 /ug=Hs.116875 /len=3788 NM_007062 Cluster Incl. L07758:Human IEF PWP1 12q24.11 SSP 9502 mRNA, complete cds /cds=(87,1592) /gb=L07758 /gi=177764 /ug=Hs.172589 /len=1853 AB011109 Cluster Incl. AB011109:Homo KIAA0537 12q24.11 sapiens mRNA for KIAA0537 protein, complete cds /cds=(1380,3365) /gb=AB011109 /gi=3043597 /ug=Hs.200598 /len=6828 NM_014301 Cluster Incl. U47101:Human NIFU 12q24.1 NifU-like protein (hNifU) mRNA, partial cds /cds=(0,366) /gb=U47101 /gi=1685101 /ug=Hs.9908 /len=819 NM_003211 Cluster Incl. U51166:Human G/T TDG 12q24.1 mismatch-specific thymine DNA glycosylase mRNA, complete cds /cds=(399,1631) /gb=U51166 /gi=1378106 /ug=Hs.173824 /len=3410 NM_005719 Cluster Incl. ARPC3 12q24 AI525393:PT1.1_07_A11.r Homo sapiens cDNA, 5 end /clone_end=5 /gb=AI525393 /gi=4439528 /ug=Hs.6895 /len=811 NM_005475 Cluster Incl. AF055581:Homo LNK 12q24 sapiens adaptor protein Lnk mRNA, complete cds /cds=(357,2084) /gb=AF055581 /gi=3845720 /ug=Hs.13131 /len=5403 NM_002973 Cluster Incl. Y08262:H.sapiens SCA2 12q24 mRNA for SCA2 protein /cds=(0,2746) /gb=Y08262 /gi=1770389 /ug=Hs.76253 /len=4163 NM_003362 Cluster Incl. Y09008:H.sapiens UNG 12q23-q24.1 mRNA for uracil-DNA glycosylase /cds=(70,1011) /gb=Y09008 /gi=1850820 /ug=Hs.78853 /len=2036 AY186578 Cluster Incl. M23114:Homo ATP2A2 12q23-q24.1 sapiens calcium-ATPase (HK1) mRNA, complete cds /cds=(163,3291) /gb=M23114 /gi=184100 /ug=Hs.1526 /len=4134 NM_003330 Cluster Incl. X91247:H.sapiens TXNRD1 12q23-q24.1 mRNA for thioredoxin reductase /cds=(439,1932) /gb=X91247 /gi=1237037 /ug=Hs.13046 /len=3826 NM_004075 Cluster Incl. D83702:Homo CRY1 12q23-q24.1 sapiens mRNA for photolyase, complete cds /cds=(586,2346) /gb=D83702 /gi=1304106 /ug=Hs.151573 /len=2981 NM_005594 Cluster Incl. AF054187:Homo NACA 12q23-q24.1 sapiens alpha NAC mRNA, complete cds /cds=(309,956) /gb=AF054187 /gi=4092059 /ug=Hs.146763 /len=1059 NM_001177 Cluster Incl. L28997:Homo ARL1 12q23.3 sapiens ARL1 mRNA, complete cds /cds=(144,689) /gb=L28997 /gi=607027 /ug=Hs.77102 /len=1008 NM_002465 Cluster Incl. X73114:H.sapiens MYBPC1 12q23.3 mRNA for slow MyBP-C /cds=(81,3452) /gb=X73114 /gi=402618 /ug=Hs.169849 /len=3764 NM_003297 Human steroid receptor NR2C1 12q23.1 (TR2-11) mRNA, complete cds NM_005888 Cluster Incl. X60036:H.sapiens SLC25A3 12q23 mRNA for mitochondrial phosphate carrier protein /cds=(48,1133) /gb=X60036 /gi=38261 /ug=Hs.78713 /len=1314 AB013382 Cluster Incl. AB013382:Homo DUSP6 12q22-q23 sapiens mRNA for DUSP6, complete cds /cds=(351,1496) /gb=AB013382 /gi=3869139 /ug=Hs.180383 /len=2390 NM_000618 Human IGF-I mRNA for IGF1 12q22-q23 insulin-like growth factor I NM_006166 Cluster Incl. NFYB 12q22-q23 AA621555:af53a04.s1 Homo sapiens cDNA, 3 end /clone=IMAGE-1035342 /clone_end=3 /gb=AA621555 /gi=2525494 /ug=Hs.84928 /len=791 NM_001682 Cluster Incl. J04027:Human ATP2B1 12q21-q23 plasma membrane Ca2+ pumping ATPase mRNA, complete cds /cds=(181,3843) /gb=J04027 /gi=950413 /ug=Hs.78546 /len=4398 NM_002345 Cluster Incl. U21128:Human LUM 12q21.3-q22 lumican mRNA, complete cds /cds=(84,1100) /gb=U21128 /gi=699576 /ug=Hs.79914 /len=1717 NM_003805 Human death domain containing CRADD 12q21.33-q23.1 protein CRADD mRNA, complete cds NM_002847 Cluster Incl. U81561:Human PTPRN2 7q36 protein tyrosine phosphatase receptor pi (PTPRP) mRNA, complete cds /cds=(42,3038) /gb=U81561 /gi=2351575 /ug=Hs.74624 /len=4699 NM_002889 Cluster Incl. U77594:Human RARRES2 7q36.1 tazarotene-induced gene 2 (TIG2) mRNA, complete cds /cds=(96,587) /gb=U77594 /gi=1848263 /ug=Hs.37682 /len=708 NM_013316 Cluster Incl. U71267:Human CNOT4 7q22-qter potential transcriptional repressor NOT4Hp (NOT4H) mRNA, complete cds /cds=(281,2209) /gb=U71267 /gi=4097897 /ug=Hs.20423 /len=3297 AF493921 Homo sapiens mRNA for RHEB2 7q36 ras-related GTP-binding protein; complete cds NM_003592 Cluster Incl. AF062536:Homo CUL1 7q36.1 sapiens cullin 1 mRNA, complete cds /cds=(124,2454) /gb=AF062536 /gi=3139076 /ug=Hs.14541 /len=2583 NM_003040 Cluster Incl. U62531:Human AE2 SLC4A2 7q35-q36 anion exchanger (SLC4A2) mRNA, complete cds /cds=(174,3899) /gb=U62531 /gi=1809029 /ug=Hs.79410 /len=4054 D13635 Cluster Incl. D13635:Human KIAA0010 7q36.3 mRNA for KIAA0010 gene, complete cds /cds=(303,3554) /gb=D13635 /gi=285982 /ug=Hs.155287 /len=5160 |