Table 3 of
Suryanarayana, Mol Vis 2004;
10:148-154.Table 3 of
Suryanarayana, Mol Vis 2004;
10:148-154.
Table 3. Kinetic parameters of rat lens and human recombinant AR in the absence and presence of tannoids of E. officinalis
Vmax is reported as μmoles NADPH oxidized/h/100 mg for rat lens AR or μmoles NADPH oxidized/min/mg for human recombinant AR. Asterisks (*) indicate a statistically significant difference from the values in the absence of tannoids (Student's t-test, p<0.001). Values are mean±standard deviation (n=5).
Rat lens AR Human recombinant AR
------------------- --------------------
Kinetic (-) (+) (-) (+)
parameter Tannoids Tannoids Tannoids Tannoids
--------- -------- -------- -------- ---------
Km (mM) 0.279 0.161* 0.085 0.037*
±0.032 ±0.022 ±0.017 ±0.013
Vmax 24.2 10.6* 3.88 1.72*
±1.57 ±1.42 ±0.219 ±0.231
|