Figure 4. Canonical roots of IgG serum antibodies against optic nerve

Canonical roots of IgG serum autoantibodies of subjects with primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), ocular hypertension (OHT), and healthy volunteers (CTRL). The analysis of discriminance is able to calculate a parameter, the so called canonical roots, as a kind of similarity index of each electrophoretic lane. This can be used to illustrate the quality of discriminance between the samples and to demonstrate the sharpness of a diagnostic criterion. The closer the canonical roots of samples are the more similar the electrophoretic patterns were.