Figure 2 of
Wang, Mol Vis 2004;
10:103-111.Figure 2 of
Wang, Mol Vis 2004;
10:103-111.
Figure 2. cDNA sequence of the cytoplasmic domain of human and murine PECAM-1 isoforms
The nucleotide sequence encoding the cytoplasmic domain of human PECAM-1 isoform lacking exon 14 is compared to the nucleotide sequence for human full-length PECAM-1 (A). The nucleotide sequence encoding the cytoplasmic domain of murine PECAM-1 isoforms lacking exon 12, 14, 15, 12&15, 14&15, or 12, 14&15 is compared to the nucleotide sequence for murine full-length PECAM-1 (B). The deleted sequences are indicated by hyphens (-). The predicated exon sequences of human and murine PECAM-1 were as described previously [27,28].
A:
Full AGG AAA GCC AAG GCC AAG CAG ATG CCA GTG GAA ATG TCC AGG CCA GCA GTA CCA CTT CTG ACC TCC Δ14 AGG AAA GCC AAG GCC AAG CAG ATG CCA GTG GAA ATG TCC AGG CCA GCA GTA CCA CTT CTG ACC TCC AAC AAC GAG AAA ATG TCA GAT CCC AAT ATG GAA GCT AAC AGT CAT TAC GGT CAC AAT GAC GAT GTC AGA AAC CAT AAC AAC GAG AAA ATG TCA GAT CCC AAT ATG GAA GCT AAC AGT CAT TAC GGT CAC AAT GAC GAT GTC GGA AAC CAT GCA ATG AAA CCA ATA AAT GAT AAT AAA GAG CCT CTG AAC TCA GAC GTG CAG TAC ACG GAA GTT CAA GTG TCC TCA GCA ATG AAA CCA ATA AAT GAT AAT AAA GAG CCT CTG AAC TCA GAC GTG CAG TAC ACG GAA GTT CAA GTG TCC TCA GCT GAG TCT CAC AAA GAT CTA GGA AAG AAG GAC ACA GAG ACA GTG TAC AGT GAA GTC CGG AAA GCT GTC CCT GAT GCT GAG TCT CAC AAA G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -AT GCC GTG GAA AGC AGA TAC TCT AGA ACG GAA GGC TCC CTT GAT GGA ACT TAG ACA GCA AGG GCC GTG GAA AGC AGA TAC TCT AGA ACG GAA GGC TCC CTT GAT GGA ACT TAG ACA GCA AGG |
B:
Full AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ12 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ14 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ15 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ12&15 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ14&15 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC Δ12,14&15 AGG AAA GCC AAG GCC AAA CAG AAA CCC GTG GAG ATG TCC AGG CCA GCT GCT CCA CTT CTG AAC CCC AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC GGT TAT GAT GAT GTT TCT GGA AAT GAT AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC G-- --- --- --- --- --- --- --- --- AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC GGT TAT GAT GAT GTT TCT GGA AAT GAT AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC GGT TAT GAT GAT GTT TCT GGA AAT GAT AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC G-- --- --- --- --- --- --- --- --- AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC GGT TAT GAT GAT GTT TCT GGA AAT GAT AAC AGC GAG AAG ATT TCT GAG CCT AGT GTG GAA GCC AAC AGC CAT TAC G-- --- --- --- --- --- --- --- --- GCA GTA AAA CCC ATA AAT CAA AAT AAA GAC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC --- --- --- --- --- --- --- --- --- -AC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC GCA GTA AAA CCC ATA AAT CAA AAT AAA GAC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC GCA GTA AAA CCC ATA AAT CAA AAT AAA GAC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC --- --- --- --- --- --- --- --- --- -AC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC GCA GTA AAA CCC ATA AAT CAA AAT AAA GAC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC --- --- --- --- --- --- --- --- --- -AC CCC CAG AAC ATG GAT GTA GAA TAC ACA GAA GTG GAA GTG TCC TCC CTT GAG CCT CAC CAA GCT CTG GGA ACG AGA GCC ACA GAG ACG GTG TAC AGT GAG ATC CGG AAG GTC GAC CCT AAT CTT GAG CCT CAC CAA GCT CTG GGA ACG AGA GCC ACA GAG ACG GTG TAC AGT GAG ATC CGG AAG GTC GAC CCT AAT CTT GAG CCT CAC CAA G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -AT CTT GAG CCT CAC CAA GCT CTG GGA ACG AGA GCC ACA GAG ACG GTG TAC AGT GAG ATC CGG AAG GTC GAC CCT AA- CTT GAG CCT CAC CAA GCT CTG GGA ACG AGA GCC ACA GAG ACG GTG TAC AGT GAG ATC CGG AAG GTC GAC CCT AA- CTT GAG CCT CAC CAA G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- CTT GAG CCT CAC CAA G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- CTC ATG GAA AAC AGA TAT TCT AGA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA CTC ATG GAA AAC AGA TAT TCT AGA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA CTC ATG GAA AAC AGA TAT TCT AGA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA --- --- --- --- --- --- --- -GA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA --- --- --- --- --- --- --- -GA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA --- --- --- --- --- --- --- -GA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA --- --- --- --- --- --- --- -GA ACG GAA GGC TCC CTT AAT GGA ACT TAA GAC AGT CAA |