Figure 8. Effect of reperfusion Number of TUNEL positive retinal ganglion cells

Mean number of TUNEL positive retinal ganglion cells (RGCs) per 250 μm length of retina section 6 h after reperfusion. There were significantly more TUNEL positive RGCs in rAAV-LacZ treated retinas (n=8) and in untreated retinas (n=8) than in rAAV-GDNF treated retinas (n=8). Groups marked with an asterisk (*) were significantly different from the rAAV-GDNF transduced group (Wilcoxon signed-ranks test, p<0.05). Groups marked with two asterisks (**) were significantly different from the rAAV-GDNF transduced group (Mann-Whitney test, p<0.05). Error bars represent the standard deviation.