Figure 1 of
Le, Mol Vis 2004;
Figure 1. Generation of HRGP-cre mice
A: Schematic drawing of the transgenic construct. HRGP labels the human red/green pigment promoter, cre labels the coding region of Cre recombinase gene, and MT-1 A(n) labels mouse metallothionein (MT-I) polyadenylation signal. B: Southern blot analysis of NcoI digested genomic DNA from two (1 and 2) representative transgenic founders. A 0.5 kb BamHI-NcoI cre DNA segment of the transgenic construct was used as probe. C: RT-PCR detection of Cre expression in two representative HRGP-cre transgenic founder mice.