Table 3 of
Paluru, Mol Vis 2004;
10:917-922.Table 3 of
Paluru, Mol Vis 2004;
10:917-922.
Table 3. Two point linkage analysis of Pedigree-2 using polymorphic microsatiellites markers at chromosomes 12q23-24 and 1q23-32
A total of 11 markers at 12q23-24 and 7 markers for 1q23-32 were used for fine point genotyping. The list displays the polymorphic microsatellite markers used for genotyping, LOD scores at theta max, nonparametric linkage (NPL) scores (model free analysis with 0.9 penetrance, 0.10 phenocopy rate), p values, and informative marker values (marker heterozygosity). The red color denotes the highest LOD scores for both chromosomal intervals.
Marker LOD score NPL score p value Information -------- --------- --------- ------- ----------- D12S346 0.336437 1.976623 0.0625 0.574837 D12S78 0.406907 2.038583 0.0625 0.740833 D12S1613 0.030702 0.855281 0.0625 0.462905 D12S1583 1.406333 2.038583 0.0625 0.745644 D12S1646 -0.001336 0.151861 0.28125 0.218872 D12S79 1.406333 2.038583 0.0625 0.734998 D12S1718 -0.000996 0 0.28125 0.10817 D12S86 1.405871 1.914664 0.0625 0.8 D12S324 1.405871 1.914664 0.0625 0.8 D12S1659 0.002513 0 0.28125 0.2 D12S1723 1.115712 0.801826 0.0625 0.527807 D1S2726 -0.267785 -0.300887 0.5 0.574837 D1S252 0.445379 0.238118 0.25 0.35 D1S484 1.406333 2.038583 0.0625 0.727807 D1S2878 1.328281 1.731621 0.0625 0.674837 D1S196 0.288437 0.595295 0.125 0.318872 D1S218 -1.470127 0.196812 0.25 0.8 D1S238 -2.449207 -0.32559 0.5625 0.7 |