Wang, Mol Vis 2004; 10:851-856. Table 1.

Table 1 of Wang, Mol Vis 2004; 10:851-856.

Table 1. MYOC and OPTN variants identified in the Philippine family

The χ² test or Fisher's exact test was used to compare the frequencies of various alleles and genotypes between JOAG and normal subjects. No polymorphism was statistically significant (p>0.05).

                                              Allele           Genotype
                                           frequency (%)       frequency
                                         -----------------   --------------
                    Sequence    Codon     JOAG     Normal    JOAG    Normal
Gene    Location     change     change   (n=18)    (n=36)    (n=9)   (n=18)
-----   --------   ----------   ------   -------   -------   -----   ------
MYOC    Exon 1     c.227G>A     R76K     3(17)     7(19.4)   0/3/6   1/5/12
        Promoter   -80G>A         -      3(17)     4(11.1)   0/3/6   1/2/15
        Promoter   -1000C>G       -      1(5.6)    3(8.3)    0/1/9   0/3/15

OPTN    Exon 4     c.412G>A     T34T     5(27.8)   6(16.7)   0/5/4   0/6/12
        Exon 5     c.603T>A     M98K     2(11.1)   5(13.9)   0/2/7   0/5/13
        Exon 16    c.1944G>A    R545Q    0(0)      3(8.3)    0/0/9   0/3/15
        Intron 7   IVS7+24G>A     -      5(27.8)   4(11.1)   0/5/4   1/2/15

Wang, Mol Vis 2004; 10:851-856 <http://www.molvis.org/molvis/v10/a102/>