Figure 6. PEDF over-expression does not prevent eventual vessel development and differentiation from taking place

A: Whole mount retina from a P21 retina injected with AAV2/1.CMV.PEDF at P2. Scale bar represents 1 mm. B: High magnification of the same whole mount showing details in capillary structure. Scale bar represents 100 μm. Experimental retinas over-expressing PEDF continue to develop, attaining a mature capillary structure and normal stratification in deeper layers of the retina by P21.