Molecular mechanisms of antisense drugs: RNase H

Antisense Nucleic Acid Drug Dev. 1998 Apr;8(2):133-4. doi: 10.1089/oli.1.1998.8.133.
No abstract available

Publication types

  • Review

MeSH terms

  • Bacterial Proteins / metabolism
  • Cloning, Molecular
  • Humans
  • Macromolecular Substances
  • Oligonucleotides, Antisense / chemistry
  • Oligonucleotides, Antisense / pharmacology*
  • Protein Binding
  • Protein Biosynthesis / drug effects
  • RNA / drug effects
  • RNA / metabolism
  • Ribonuclease H / genetics
  • Ribonuclease H / metabolism*
  • Species Specificity
  • Structure-Activity Relationship
  • Transcription, Genetic / drug effects

Substances

  • Bacterial Proteins
  • Macromolecular Substances
  • Oligonucleotides, Antisense
  • RNA
  • Ribonuclease H