Cyanate-induced cataracts in patients with sickle-cell hemoglobinopathies

Arch Ophthalmol. 1976 Jun;94(6):927-30. doi: 10.1001/archopht.1976.03910030465005.

Abstract

Two young patients developed bilateral posterior subcapsular cataracts while receiving oral sodium cyanate for treatment of sickle cell hemoglobinopathy. In one of the patients, lens opacities regressed spontaneously after cyanate therapy was discontinued.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Oral
  • Adult
  • Anemia, Sickle Cell / complications
  • Anemia, Sickle Cell / drug therapy*
  • Anemia, Sickle Cell / pathology
  • Cataract / chemically induced*
  • Cataract / pathology
  • Cyanates / adverse effects*
  • Cyanates / therapeutic use
  • Dose-Response Relationship, Drug
  • Humans
  • Lens, Crystalline / pathology
  • Male
  • Ophthalmoscopy
  • Remission, Spontaneous
  • Thalassemia / drug therapy
  • Visual Acuity / drug effects

Substances

  • Cyanates