TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins

R Knüppel; P Dietze; W Lehnberg; K Frech; E Wingender

doi:10.1089/cmb.1994.1.191

TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins

J Comput Biol. 1994 Fall;1(3):191-8. doi: 10.1089/cmb.1994.1.191.

Authors

R Knüppel¹, P Dietze, W Lehnberg, K Frech, E Wingender

Affiliation

¹ Gesellschaft für Biotechnologische Forschung, Department of Genetics, Braunschweig, Germany.

PMID: 8790464
DOI: 10.1089/cmb.1994.1.191

Abstract

DNA sequences that are involved in the control of gene expression in eukaryotes have been collected in conjunction with the proteins binding to and acting through them (TRANSFAC data set). To make these data accessible, the TRANSFAC retrieval program (TRP) has been developed as a database management system which is based upon the network model. This database model possesses particular advantages for data management of a complex structure. The aim of TRP is to provide an easily handled statistical basis for a computational approach to transcription control.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
Database Management Systems*
Databases, Factual*
Regulatory Sequences, Nucleic Acid*
Transcription Factors*
Transcription, Genetic*
User-Computer Interface

Substances

Transcription Factors