Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

Cancer Res. 1994 Sep 15;54(18):4855-78.
No abstract available

Publication types

  • Review

MeSH terms

  • Aflatoxins / toxicity
  • Animals
  • Cell Transformation, Neoplastic / genetics
  • Chromosome Deletion
  • Conserved Sequence
  • DNA Damage
  • DNA Mutational Analysis
  • DNA Repair
  • DNA Replication
  • Disease Models, Animal
  • Genes, p53 / genetics*
  • Genes, p53 / physiology
  • Hepatitis B / complications
  • Humans
  • Mutation / genetics*
  • Neoplasms / etiology
  • Neoplasms / genetics*
  • Neoplasms, Radiation-Induced / genetics
  • Phenotype
  • Sequence Analysis, DNA
  • Smoking / adverse effects
  • Structure-Activity Relationship
  • Tumor Suppressor Protein p53 / chemistry
  • Tumor Suppressor Protein p53 / physiology

Substances

  • Aflatoxins
  • Tumor Suppressor Protein p53