The sorbitol pathway and the complications of diabetes

N Engl J Med. 1973 Apr 19;288(16):831-6. doi: 10.1056/NEJM197304192881609.
No abstract available

Publication types

  • Review

MeSH terms

  • Alcohol Oxidoreductases / analysis
  • Alcohol Oxidoreductases / metabolism
  • Animals
  • Carbohydrate Metabolism
  • Cataract / etiology
  • Cataract / metabolism
  • Central Nervous System / enzymology
  • Central Nervous System / metabolism
  • Diabetes Complications*
  • Diabetes Mellitus / chemically induced
  • Diabetes Mellitus / physiopathology
  • Diabetic Neuropathies / enzymology
  • Diabetic Neuropathies / etiology
  • Diabetic Neuropathies / metabolism*
  • Glucose / metabolism
  • Humans
  • In Vitro Techniques
  • Lens, Crystalline / metabolism
  • Neural Conduction
  • Peripheral Nerves / enzymology
  • Peripheral Nerves / metabolism
  • Rats
  • Sorbitol / metabolism*
  • Streptozocin

Substances

  • Sorbitol
  • Streptozocin
  • Alcohol Oxidoreductases
  • Glucose