Unusual inclusions in stromal macrophages in a case of gelatinous drop-like corneal dystrophy

Am J Ophthalmol. 1985 Mar 15;99(3):312-6. doi: 10.1016/0002-9394(85)90361-7.

Abstract

A 35-year-old man developed gelatinous drop-like corneal dystrophy at age 20. Amyloid deposits were located mainly in the anterior two thirds of the cornea. Ultrastructurally, amyloid fibrils were demonstrated beneath the corneal epithelium and in the cytoplasmic inclusions of the stromal macrophages.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyloid / metabolism
  • Cornea / metabolism
  • Cornea / ultrastructure*
  • Corneal Dystrophies, Hereditary / metabolism
  • Corneal Dystrophies, Hereditary / pathology*
  • Cytoskeleton / ultrastructure
  • Histocytochemistry
  • Humans
  • Inclusion Bodies / ultrastructure*
  • Macrophages / metabolism
  • Macrophages / ultrastructure*
  • Male

Substances

  • Amyloid