Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state

Burns. 1989 Oct;15(5):303-9. doi: 10.1016/0305-4179(89)90007-7.

Abstract

This report describes the clinical results obtained from a multicentre experience of the use of autologous and allogenic cultured human epidermal cells in the treatment of partial and full skin thickness burns. A laboratory has been organized to supply cultured epithelium to Burns Units in different cities. From May 1986 to December 1988, 58 patients with an age range of 1 to 59 years, and with burns covering between 7 and 95 per cent of the body surface area, have been treated. Graftable cultured epithelium can be frozen and remain viable if stored in a skin bank. Such grafts were used successfully to treat patients with partial and full skin thickness wounds.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Bandages*
  • Biological Dressings*
  • Burns / pathology
  • Burns / surgery*
  • Child
  • Child, Preschool
  • Culture Techniques
  • Freezing
  • Graft Survival
  • Humans
  • Infant
  • Microscopy, Electron
  • Middle Aged
  • Multicenter Studies as Topic
  • Postoperative Complications / pathology
  • Skin / pathology
  • Skin Transplantation*
  • Tissue Preservation
  • Wound Healing