Assignment of the alpha B-crystallin gene to human chromosome 11

Genomics. 1989 Nov;5(4):665-9. doi: 10.1016/0888-7543(89)90106-7.

Abstract

Using a human alpha B-crystallin genomic probe and human-mouse somatic cell hybrids, the human alpha B-gene was assigned to chromosome 11 and further corroborated by in situ hybridization to normal metaphase chromosomes. This assignment confirmed and regionally mapped the locus to q22.3-23.1.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blotting, Southern
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 11*
  • Crystallins / genetics*
  • Humans
  • Hybrid Cells
  • Mice

Substances

  • Crystallins