Cytogenetic findings in six posterior uveal melanomas: involvement of chromosomes 3, 6, and 8

Genes Chromosomes Cancer. 1990 Sep;2(3):205-9. doi: 10.1002/gcc.2870020307.

Abstract

Six posterior uveal melanomas were karyotyped after short-term culture. One had a normal chromosome complement; the remaining five had limited chromosome changes. Involvement of chromosomes 1 and 6 was noted in two and four cases, respectively, and three ciliary body tumours demonstrated both monosomy 3 and i(8q).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cells, Cultured
  • Chromosome Aberrations*
  • Chromosome Deletion
  • Chromosome Disorders*
  • Chromosomes, Human, Pair 3*
  • Chromosomes, Human, Pair 6*
  • Chromosomes, Human, Pair 8*
  • Humans
  • Karyotyping
  • Melanoma / genetics*
  • Melanoma / pathology
  • Metaphase
  • Middle Aged
  • Uveal Neoplasms / genetics*
  • Uveal Neoplasms / pathology