Abstract
Recent studies indicate that endocytic organelles can play a more active role in signal propagation and amplification than was recognised before. By deciphering the interplay between endocytosis and signalling, we will be able to gain a more sophisticated level of understanding of signal transduction mechanisms.
MeSH terms
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Animals
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Endocytosis*
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Endosomes / metabolism*
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Epidermal Growth Factor / metabolism
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ErbB Receptors / metabolism
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GTP-Binding Proteins / metabolism
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Humans
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Ligands
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Lysosomes / metabolism
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Models, Biological
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Nerve Growth Factor / metabolism
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Protein Transport
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Receptors, G-Protein-Coupled / metabolism
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Receptors, Transforming Growth Factor beta / metabolism
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Signal Transduction*
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Transforming Growth Factor beta / metabolism
Substances
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Ligands
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Receptors, G-Protein-Coupled
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Receptors, Transforming Growth Factor beta
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Transforming Growth Factor beta
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Epidermal Growth Factor
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Nerve Growth Factor
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ErbB Receptors
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GTP-Binding Proteins